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Breast Oncology Tumor Board

Sat, Apr 25, 2026 · 07:30 · Conference Room A

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Case 1 of 10 · 0 discussed

0 of 10 presented

Ibrahim, Arthur

MRN-001012·53y

Presenting

Dr. Sarah Martinez

Invasive Ductal Carcinoma, HER2+·Stage IIIA
BiomarkersER−/PR−/HER2+ · Ki-67 35%
HistologyInvasive ductal carcinoma · Grade G1
Path StagepT3N1M0
MarginsPositive at posterior margin
Key LabsHemoglobin 10.6Platelets 301
Prior TxPostmenopausal

Highlighted Path

Ibrahim, Arthur

Invasive ductal carcinoma · Stage IIIA · ER-/PR-/HER2+ (IHC 3+), Ki-67 35%, FISH amplified

NCCN Breast Cancer

v4.2025

Breast Cancer
DCIS (Non-invasive)
Stage 0
Lumpectomy → ± WBRT → ± Endocrine
Mastectomy → ± Endocrine
Invasive
Early Stage (I–IIA)
HR+/HER2−
Surgery → Endocrine ± Chemo
HR+/HER2+
Surgery → TCH(P) → Endocrine
HR−/HER2+
Surgery → TCH(P)
Triple Negative
Surgery → AC-T
Locally Advanced (IIB–III)
HR+/HER2−
Neoadjuvant Chemo → Surgery → Endocrine
HER2+
Neoadjuvant TCHP → Surgery → HER2 maintenance
Triple Negative
Neoadjuvant Chemo + Pembrolizumab → Surgery
Metastatic (IV)
HR+/HER2−
Endocrine + CDK4/6i (1L)
HER2+
Taxane + Trastuzumab + Pertuzumab (1L)
Triple Negative
Chemo + Pembrolizumab (PD-L1+)
Patient pathway Other pathways
12 treatment approaches mapped
Case 1 of 1000:00
Clinical question

Dose reduction strategy for AI-related arthralgia affecting treatment compliance.

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